KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F8
All Species:
13.33
Human Site:
S664
Identified Species:
36.67
UniProt:
A0AVK6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AVK6
NP_078956.2
867
94166
S664
K
E
N
S
S
A
L
S
P
N
H
R
I
Y
S
Chimpanzee
Pan troglodytes
XP_508325
867
94169
S664
K
E
N
S
G
A
L
S
P
N
H
R
I
Y
S
Rhesus Macaque
Macaca mulatta
XP_001095088
867
94195
S664
K
E
N
S
G
A
L
S
P
N
H
R
I
Y
S
Dog
Lupus familis
XP_534087
864
93661
T661
S
S
K
E
N
S
S
T
L
S
P
N
H
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q58FA4
860
93258
G657
L
S
N
T
E
N
S
G
T
P
S
P
N
H
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506156
878
95490
S675
K
E
S
P
G
S
C
S
P
T
P
R
I
Y
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084876
724
79575
R522
D
D
Q
S
T
Q
E
R
G
P
K
R
Q
H
E
Zebra Danio
Brachydanio rerio
XP_694311
917
100437
T715
L
P
S
G
P
I
H
T
E
T
L
I
P
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321561
384
43173
L182
S
N
A
N
L
I
S
L
D
E
S
A
K
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.6
89.6
N.A.
83
N.A.
N.A.
73.8
N.A.
48
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.1
94.2
N.A.
88.5
N.A.
N.A.
82.1
N.A.
59.9
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
6.6
N.A.
N.A.
46.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
26.6
N.A.
20
N.A.
N.A.
66.6
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
30.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
34
0
0
0
0
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
45
0
12
12
0
12
0
12
12
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
34
0
0
12
12
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
12
0
0
0
34
0
12
23
0
% H
% Ile:
0
0
0
0
0
23
0
0
0
0
0
12
45
0
12
% I
% Lys:
45
0
12
0
0
0
0
0
0
0
12
0
12
0
0
% K
% Leu:
23
0
0
0
12
0
34
12
12
0
12
0
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
45
12
12
12
0
0
0
34
0
12
12
0
12
% N
% Pro:
0
12
0
12
12
0
0
0
45
23
23
12
12
0
0
% P
% Gln:
0
0
12
0
0
12
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
56
0
12
12
% R
% Ser:
23
23
23
45
12
23
34
45
0
12
23
0
0
0
34
% S
% Thr:
0
0
0
12
12
0
0
23
12
23
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _